Assays for potentially anticarcinogenic phytoehemicals in flaxseed.

January 1, 1993 Human Health and Nutrition Data 0 Comments

Assays for potentially anticarcinogenic phytoehemicals in flaxseed.

Year: 1993
Authors: R K Harris, W J Haggerty.
Publication Name: Cereal Foods World
Publication Details: Volume 38; Number 3; 147.


Lignans in flaxseed have been reported to have a number of biological activities that include antitumor, antimitotic, antiviral, enzyme inhibition, nucleic acid synthesis inhibition and estrogenic and anti-estrogenic effects. Lignans in flaxseed occur as secoisolariciresinol and secoisolariciresinol diglycoside which are converted in the human intestine into the mammalian lignans enterodiol and enterolactone. This article focuses on methods developed to extract and quantify lignans and phenolic acids in flaxseed flour and on techniques that can be used to assess the storage stability of flaxseed flour. The methods involve two procedures to isolate lignans and subsequently identify them by high performance liquid chromatography and thin layer chromatography. Estimated levels (?g/g) of lignans in fresh and aged (9 months storage at -20? C) flaxseed four were reported, respectively, as chlorogenic acid: 7.5 and 6.0; ferulic acid: 10.9 and 11.4; gallic acid: 2.8 and 1.9 and SDG: 0.7 and 0.9.

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