Lignans from Linum species of sections Syllinum and Linum

January 1, 2007 Human Health and Nutrition Data 0 Comments

Lignans from Linum species of sections Syllinum and Linum

Year: 2007
Authors: Konuklugil, B., Ionkova, I., Vasilev, N., Schmidt, T.J., Windhövel, J., Fuss, E., Alfermann, A.W.
Publication Name: Natural Product Research
Publication Details: Volume 21; Number 1; Pages 1–6


The aryltetralin lignans 6-methoxypodophyllotoxin, 5'-demethoxy-6-methoxypodophyllotoxin as well as the corresponding 8'-epimers 6-methoxypicropodophyllin, and 5'-demethoxy-6-methoxypicropodophyllin were isolated from suspension cultures of Linum cariense, and 4'-demethyl-6-methoxypodophyllotoxin together with 6-methoxypodophyllotoxin from plants of L. tauricum, which both belong to section Syllinum of the genus Linum. Cell cultures of L. altaicum, L. austriacum ssp. euxinum and L. lewisii belonging to section Linum accumulate the naphthalene lignans justicidin B and isojusticidin B. The different lignans were identified by HPLC and spectroscopic methods. Author's Abstract.

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